world. half of that goes out to grants in every state of the nation. when you hear about a breakthrough that has happened in diabetes research or autism or alzheimer's, it is very likely that it came from a university or institute somewhere that was supported by nih. that is what we do. we support the best and brightest to chase after their visionary ideas, and we think we are good at that. >> what is the influence? as the director, with 27 institutes and centers, how do you influence what goes on? >> it is a very big place. it has 27 institutes and centers. they are various diseases- or organ-instance focused. -- organ-system focused. there is a cancer institute, a diabetes institute, a heart and lung institute. each of these is led by remarkable, world-class scientists. they work across the landscape to try to identify what has to happen next in order to advance human health.